Orthostatic Proteinuria

Orthostatic proteinuria occurs in between 2-5% of all adolescents–it is primarily a pediatric condition, rarely occurring after age 30. Orthostatic proteinuria refers to the condition of an individual having proteinuria only while upright; the urine protein level returns…

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Treatment of Acute Hyperkalemia

This is probably review as it is such a common occurrence for nephrologists as well as internists. Here’s my protocol, along with useful dosing info (sometimes lacking in textbooks): 1. Get an EKG. Look to see if there…

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“The Catheter Epidemic”

In the most recent issue of C-JASN there is an intriguing article entitled “Ethical and Legal Obligation To Avoid Long-Term Tunneled Catheter Access” by Rehman et al, in which the authors argue strongly that tunneled catheters should be…

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History of Renal Biopsy

Who was the first doctor to have the idea (and the audacity) to stick a needle into the kidney in order to obtain a tissue diagnosis of kidney disease?  The “inventors of the renal biopsy” have been identified…

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Renal effects of licorice

Licorice–particularly European licorice which contains higher doses of the natural sweetener glycyrrhizic acid (GZA)–needs to be considered in the differential diagnosis of hyperaldosteronism. Here’s how it works: The mineralocorticoid receptor, expressed in cortical collecting duct cells, is the…

Thiazolidinediones: Not just for diabetes?

The thiazolidinediones (a.k.a. “the glitazones”) are widely used in the treatment of of hyperglycemia. Although they have their side effects (an increased risk of cardiac events according to some epidemiologic studies, plus the possibility of fluid overload or…

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microRNAs and the Kidney

MicroRNAs: one of the sexiest topics in the science community these days! Pick up a copy of Science, Nature, or Cell and you can usually find something to do with microRNAs within. What do these have to do…

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Happy Presidents Day

In honor of Presidents Day I did a quick search to see if any U.S. Presidents suffered from kidney ailments. The name I keep running across is Chester A. Arthur, the 21st President of the U.S., who is…

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Links from Other Nephrology Blogs

A few links for today, borrowing heavily from other Nephrology Blogs: There is an interesting interchange on Kidney Notes responding to some highly negative comments made about the field of Nephrology by a practicing nephrologist “Nephrogirl.” The Precious…

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