One of my mentors, Dr. Fred Silva, frequently reminds us that “the kidney has a limited number of ways to respond to an innumerable number of injuries”. For this reason, studying kidney pathology is challenging and fun. Since…
Autosomal dominant polycystic kidney disease (ADPKD) is a common genetic disease, affecting 1/400 to 1/1000 live births and is the fourth leading cause of end-stage kidney disease in adults. Both types of ADPKD (1 and 2) typically have…
The UK Renal Association SpR Club and Kidney Research UK are delighted to invite you to their Spring meeting for 2019 – ‘Updates in Nephrology’. This will be held on March 16-17th in the beautiful city of Edinburgh….
Anorexia nervosa is characterized by caloric restriction and pathologic behaviors to achieve weight loss, such as excessive exercising, dieting, or purging (e.g. abuse of laxatives or diuretics, surreptitious vomiting). Patients with bulimia nervosa engage in purging behaviors and…
Hyperkalemia is a common complication after organ transplantation, that resultins from several factors, including medications. Although the exact mechanism is unclear, calcineurin inhibitors (CNI), such as tacrolimus and cyclosporin, have been hypothesized to cause hyperkalemia through inhibitory effects…
Acquired Cystic Kidney Disease in the ESKD population Acquired cystic kidney disease (ACKD) was first described in 1847 by Simon while studying patients with glomerulonephritis (Bright’s Disease). However, it was not until 1977 when ACKD was “rediscovered” by…
Waxy casts are found during microscopic examination of the urinary sediment. Like other casts, they are cylindrical structures, but they are distinctly characterized by a high refractive index. Their shape can be straight (Fig. 1A, top cast), convoluted (Fig….
Encapsulating Peritoneal Sclerosis (EPS) is an extremely rare, but devastating possible complication of peritoneal dialysis. The International Society of Peritoneal Dialysis (ISPD) defines it as a “syndrome continuously, intermittently, or repeatedly presenting with symptoms of intestinal obstruction caused…
We’re excited to begin sharing posts from the Rewind section of ASN Communities. Below is a post from Mark Lerman, MD, FASN, originally posted 7/8/18. Enjoy! IntroductionA patient is scheduled for an ABO incompatible kidney transplant. He is…
Introduction The surgical technique for creating an arteriovenous fistula (AVF) has existed since 1966. AVFs are the recommended vascular access for end stage kidney disease patients who require dialysis, but only 14% of patients in the United States…