Anti-Nephrin Antibodies in Minimal Change Disease
Approach to the Patient with Peritoneal Dialysis Catheter Dysfunction- Part 1
Want to write a case report? RFN has you covered with a list of journals to choose from
Have a Nephrology Question? There Might Be A #Tweetorial For That!
Conferences, Courses, & Grants
FOAMed
Interventional Nephrology Series
Focus on Point-of-Care Ultrasound in Nephrology (POCUN) Series
Kidney Biopsy of the Month Series
NephJC Live at ASN Kidney Week 2014
The Nephrology twitter journal club will come to life on Saturday 15th November at Kidney Week in Philadelphia. NephJC co-founders Dr Joel Topf and Dr Swapnil Hiremath will co-host the event at the Double Tree hotel. There will…
Preventing PD Peritonitis: What’s the Evidence?
Peritoneal dialysis associated peritonitis is the second commonest cause of death among PD patients (35/1000 years) and the most common cause of treatment failure. It confers a CV risk of 7 times normal for 6 months following the…
SEVERE CHRONIC HYPONATREMIA: A Pathophysiological Rumination.
PART 4: CONTROL ISSUES 1. Losing Control: In the preceding posts, I explained how sudden emergence of water diuresis as the predominant mechanism by which rapid overcorrection of serum sodium happens in cases of severe chronic hyponatremia. Few…
FSGS biomarker updates—suPAR, B7-1, CD40 and more…
FSGS is the most common glomerular disorder causing end-stage kidney disease in the USA with a high post-transplant recurrence rate of 20-50%. Furthermore, the treatment of post-transplant recurrent FSGS is extremely challenging. While reading a recent article on…
SEVERE CHRONIC HYPONATREMIA: A Pathophysiological Rumination (Part 3)
PART 3: THE DANGERS OF “DEPLETION” In my previous post concerning chronic severe hyponatremia, I explained how over corrections of serum sodium of large magnitude required a dilute large volume diuresis, often precipitated by resolution of a transient…
SEVERE CHRONIC HYPONATREMIA: A Pathophysiological Rumination (Part 2)
PART 2: THE PEE IS THE KEY I mentioned in the previous post that severe hyponatremia is multifactorial and that the contributing etiological factors in any given case may be transient and reversible. In this post I would…
SEVERE CHRONIC HYPONATREMIA: A Pathophysiological Rumination (Part 1)
INTRODUCTION: Severe chronic hyponatremia (<120 mEq/L) remains the #1 reason nephrologists lose sleep on call nights and rightly so. The fear of overcorrection and the risk of central pontine myelinolysis (CPM) or osmotic demyelination syndrome (ODS), however uncommon…
No more folic acid
Although tangetial to nephrology in some ways, I believe a recent study published in JAMA Internal Medicine has important lessons for anyone involved in clinical medicine and should make us think about the things that we do reflexively…
Renal Physiology PenCasts
Improving preclinical nephrology education during medical school is a hot topic in nephrology these days. John Roberts, a nephrology fellow at Duke, recently produced a collection of short (10-15min) videos on renal physiology in an effort to do…
NephroCheck®—can we predict AKI in the ICU? And then what?
Nephrologists have been looking for sensitive biomarkers to predict AKI. Efforts have been made and the idea of “renal angina” was proposed by Goldstein and Chawla in 2010, but still there has been no reliable biomarker commercially available…