Anti-Nephrin Antibodies in Minimal Change Disease
Approach to the Patient with Peritoneal Dialysis Catheter Dysfunction- Part 1
Want to write a case report? RFN has you covered with a list of journals to choose from
Have a Nephrology Question? There Might Be A #Tweetorial For That!
Conferences, Courses, & Grants
FOAMed
Interventional Nephrology Series
Focus on Point-of-Care Ultrasound in Nephrology (POCUN) Series
Kidney Biopsy of the Month Series
Which thiazide? – the debate continues
The debate about which thiazide diuretic to prescribe patients with hypertension has been going on for years without resolution and both HCTZ and chlorthalidone have their supporters. This topic has been discussed in the past on the blog…
New potential drug targets in ADPKD
Currently there is no good treatment for the most common inherited cause of ESRD, adult polycystic kidney disease. There have been a number of high profile trials in ADPKD in recent years. These trials have endeavored to show…
Is it time to wake up to online Hemodiafiltration?
There has been a lot of interest recently in online Hemodiafiltration (olHDF) with multiple studies published in the past year. It is a technique which has gained favor in Europe (albeit with a lack of hard evidence) while…
Bad Odor
Cystinosis is an autosomal recessive disease caused by a mutation in CTNS, which encodes the lysosomal transporter of cystine. This leads to intracellular cystine accumulation which leads to renal, neurological and cardiac damage. The treatment for this condition…
Image of the Month – Pathology
A woman in her early 30s presented to the renal clinic with sudden onset edema. Her urinalysis revealed 4+ protein and 3+ blood. Dysmorphic red cells were noted on microscopy. Apart from her edema, she had no other…
Origins of Renal Physiology
Every year we like to publicize the MDIBL origins of renal physiology course. This is a great opportunity for renal fellows and the fact that it is free apart from transportation costs is a huge bonus. This is…
Skin Lesions in Dialysis – Part 5
Nail changes in renal failure: Half and half nails (Lindsay’s nails) can be found in patients with any degree of azotemia. The prevalence is about 21% in dialysis patients. the proximal half of the nail is white and…
Skin Lesions in Dialysis – Part 4
Acquired Perforating Dermatoses: Perforating dermatoses are a group of conditions characterized by transepidermal elimination of dermal material (collagen, elastic tissue or necrotic connective tissue) (CMAJ). APD is one of the 4 major perforating disorders: Reactive perforating collagenosis (inherited…
Skin Lesions in Dialysis – Part 3
Nephrogenic Systemic Fibrosis (NSF) No post or summary on skin disorders in renal failure can omit NSF. This has been mentioned in multiple previous posts on RFN – although never summarized: The first cases of this disorder were…
Electrolyte Disorders involving Tubular Channels
Though adult nephrologists infrequently encounter these disorders in clinic, the Board Exam loves them. Below a short table describing some of these gain- and loss-of-function channel disorders that are worth remembering. The diuretic-targeted channels are shown under parenthesis…