One of the issues surrounding the study of bardoxolone in animal models was that, because of the way that it is metabolized in rats and mice, it is highly toxic when given for long periods. This specific toxicity…
JAMA has a new platform called the JAMA Network Reader that you can use to get access to content from any of the JAMA journals (includes what were formerly called Archives of …). All the content (which includes…
Phototoxic skin disorders in renal failure: Patients with renal failure or ESRD secondary SLE can have a photosensitive skin rash. For example: Discoid Lupus Erythematosus (DLE); these lesions are thick and scaly, plug the hair follicles, appear usually…
With the results of the eAJKD brackets posted by Gearoid, I thought this article might be pertinent to stimulate further the debate… This article just came out on Transplantation and is a well designed study in which the…
These are my brackets for the eAJKD nephmadness. My winner is a number 10 seed coming out of left field. For me, the importance of the MDRD trial is that it highlighted the high prevalence of CKD in…
Nephrology grand rounds in Duke University Medical Center this week inspired me to write this blog on a subject I now realise that I am weak on. Patients on dialysis are a unique group in whom we see…
Check out Nephrology Madness Sunday 3/17/13 on eAJKD. They are pitting the top advances in nephrology against each other.
The incidence of auto-immune diseases has dramatically increased in the past 50 years and the concern that environmental exposures have contributed to this increase is broadly suspected. However, it is very hard to pin-point to an individual factor. …