ACE-inhibitor induced hyponatremia

I’ve always been skeptical about ACE inhibitors as a cause of hyponatremia, despite there being almost 20 case reports of this complication in the literature. Given the fact that so many patients I see are taking an ACE…

The power of T

A talk recently about the HIM study at MGH (Hypogonadism In Men, Clin trial NCT00114114) prompted me to wonder about testosterone from the renal perspective. Testosterone is important for several aspects of male health, including fertility, bone density,…

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Bone pain after transplant

Keeping the bone theme: A 50-year-old woman with ESRD secondary to PKD  underwent a living related-kidney transplant one-month prior. At clinic visit, she was complaining of severe throbbing pain in her hands and feet. The pain was worse…

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ARBs and Cancer Risk?

In the summer of 2010, I came across a health report on the national news that was titled “Angiotensin Receptor Blockers Linked to Cancer”.  The headline was based on a publication that demonstrated an increased cancer signal associated…

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Orthostatic hypertension and strokes

That’s right you read the title correctly- it reads orthostatic hypertension and not hypotension.  Ordering orthostatics on patients is quite common.   Most of the time the clinical query is in regards to the latter (hypotension).  My mentor,…

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