Anti-Nephrin Antibodies in Minimal Change Disease
Approach to the Patient with Peritoneal Dialysis Catheter Dysfunction- Part 1
Want to write a case report? RFN has you covered with a list of journals to choose from
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Conferences, Courses, & Grants
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Interventional Nephrology Series
Focus on Point-of-Care Ultrasound in Nephrology (POCUN) Series
Kidney Biopsy of the Month Series
Pregnancy in the Dialysis Patient
While recently reading about hypogonadism in the dialysis population, I came across this review on the pregnancy outcomes in women on dialysis, summarizing observational studies published between 1995 and 2009. I have participated in only a few pregnancy-planning…
Pendrin – role in distal bicarbonate secretion
There are two major types of intercalated cell in the collecting duct of the nephron – the alpha and beta intercalated cells. We are probably most familiar with the alpha intercalated cells in terms of acid-base handling by…
Measures of dialysis dose
As previously discussed on RFN, the urea Kt/V is a measure of dialysis dose that is related to patient outcome. There are several different Kt/Vs encountered in the dialysis literature. spKt/V = single pool eKt/V = equilibratedstdKt/V =…
Cut out the salt
Cutting back your salt intake is an effective way to reduce systolic and diastolic blood pressure and decrease your risk of dying from cardiovascular disease. The current guidelines suggest that we should reduce our dietary sodium intake to…
Whole Lot of Pressure
The maintenance of mean arterial pressure to prevent tissue dysoxia and conserve organ function is central to the management of the critically ill. In patients with increased capillary permeability this is often achieved by administration of large volumes…
Fabry’s Disease – modes of inheritance
Just a quick piece to review the inheritance pattern of Fabry’s disease, a relatively rare, but under-recognized cause of End-Stage Kidney Disease in adults. Fabry’s disease is an X-linked recessive disease, caused by a defect in the gene…
Primer on Posterior Urethral Valves
As usually happens when the renal fellows help with the medical student nephrology block, I found myself confronted last week with questions I couldn’t answer. One involved the pathophysiology of posterior urethral valves (PUV), which came up in…
Take one glass of water, three times a day…
As mentioned previously by Nate, there is some evidence that lowering urine osmolarity below that of the serum can reduce the rate of growth of cysts in PCKD and thus preserve renal function. The rationale for this is…
Please Take a Moment To Remember Nate Hellman
Please take a moment today to remember our dear friend and colleague Nate Hellman, founder of Renal Fellow Network, who died tragically on this day last year. Our thoughts go out to his family, especially his wife, Claire, his two…
Try this in clinic…
It was the usual sort of day in clinic and the team was seeing a middle aged woman with stable diabetic nephropathy and subnephrotic proteinuria. Her blood pressure and blood sugars had been well controlled since the last…