Anti-Nephrin Antibodies in Minimal Change Disease
Approach to the Patient with Peritoneal Dialysis Catheter Dysfunction- Part 1
Want to write a case report? RFN has you covered with a list of journals to choose from
Have a Nephrology Question? There Might Be A #Tweetorial For That!
Conferences, Courses, & Grants
FOAMed
Interventional Nephrology Series
Focus on Point-of-Care Ultrasound in Nephrology (POCUN) Series
Kidney Biopsy of the Month Series
Shaken not stirred…
Not long ago while on call I received a midnight consult for hyperkalemia. The patient had a history notable for CLL, who was electively admitted to for induction chemotherapy. Prior to this admission, he had received no previous…
Femoral versus Jugular, part two
I have always been told that the jugular veins are preferable over the femoral veins when inserting temporary dialysis catheters. Various reasons are put forward for this including increased risk of infection and poor function of femoral catheters…
Hot peppers for hypertension?
An interesting article was published in the August 4th edition of Cell Metabolism. I’m always intrigued when common food ingredients are used to modulate biological systems. This article explores the effect of capsaicin on blood vessel tone. Capsaicin…
Doc, I am very sensitized!
Another day of transplant clinic… I heard from my attending that a couple is here for a second opinion about a kidney transplant. The husband is a 60 yo male with ESRD 2/2 PKD who had a previous…
Tubulointerstitial disease
ANATOMYThe tubulointerstial tissue is composed of cortex and medulla. The cortex has type 1 cells resembling fibroblasts and produces Epo. Type 2 cells in the cortex resemble dendritic cells capable of Ag presentation. Furthermore the cortex contains types…
Should we give up on anti-B-cell antibody therapy in the treatment of lupus nephritis?
For those of us managing patients with active lupus nephritis, the promise of a safe new therapy five years ago – anti-CD20 monoclonal antibody therapy against B cells- seemed like a breath of fresh air. A number of…
Mmm, let’s try rituximab
Mixed cryoglobulinemia (MC) is a systemic vasculitis in which B cell clones produce IgM with rheumatoid factor activity. The disease can range in severity from isolated skin lesions to full blown renal and neurological involvement. Most patients are…
Water treatment in dialysis- more than a Brita filter
And now for something totally exciting—a post on water treatment in dialysis. Dr Daniel Coyne of Washington University gave a great review on this topic at the Brigham Renal Board Review course this week. Here is the basic…
Adult-Onset dense deposit disease
We recently saw a case of adult-onset dense deposit disease (DDD) at pathology conference. DDD is rare, affecting 1-3 per million people. For historical reasons it has been classified under the membranoproliferative subgroup of disease patterns (as type…
Warfarin-induced AKI
We have recently posted about problems using warfarin in renal patients. On a similar note, I was recently involved in the care of a 58-year-old African-American patient who presented with oliguric AKI and a supratherapeutic INR level of…