Anti-neutrophil cytoplasm antibody (ANCA) was first described in 1982 in a case of segmental necrotizing glomerulonephritis (Fig. 1). The first international ANCA workshop in 1989 delineated a standard immunofluorescence technique to test for ANCA in kidney biopsy specimen….
When: August 17–24, 2019Location: MDI Biological Laboratory (travel information)For: Nephrology Fellows Origins of Renal Physiology is entirely unique among national renal short courses. The course provides participants with research tools that give them a deeper understanding of concepts…
I’m a first-year nephrology fellow who is very passionate about medical education. As a fellow at a large academic center, I have the opportunity to work closely with trainees from multiple levels and play an integral role in…
Last month, we focussed on the renal cortex in the tubulointersitium, as part of the Kidney Biopsy of the Month: What is Normal series. We will now concentrate on the renal medulla, a region of the kidney sometimes…
Literature shows that over half of the patients admitted to the intensive care unit (ICU) will eventually develop some degree of acute kidney injury (AKI). The development AKI imparts significant repercussions to both the acute and long term…
NephMadness has begun! Submit your 2019 NephMadness picks here.We’ll review some NephMadness basics below and leak our picks for this year. 1.What is NephMadness? NephMadness is an educational game played out across social media, modeled after the US…
The use of urine sediment analysis is important for the diagnosis of glomerular hematuria. Red blood cells (RBC) casts, beautifully illustrated by @jrseltzer in last month’s post, usually confirm glomerular hematuria – but this is a rather special…
“You’ll come to learn a great deal if you study the insignificant in depth” ― Odysseus Elytis In kidney transplant recipients, serum creatinine (SCr) remains the mainstay of allograft function assessment. Biopsy is the gold standard to diagnose…
Despite tremendous advancements in transplant and immunosuppressive therapy, transplantation in sensitized patients remains a major challenge. The presence of pre-transplant donor-specific antibodies (DSA) is strongly associated with poor outcomes, hyperacute, and antibody-mediated rejection. Sensitization can occur through blood…
I commonly encounter two questions from patients with chronic kidney disease (CKD) in regards to anemia: “How can I avoid taking injections?” “Is this anemia treatment safe” The development of anemia represents a challenging problem in patients with…