The American Society of Nephrology (ASN) announced the creation of a “fellow’s” website today. You can locate this site by following the link or going to the “training” tab of the main ASN website (www.asn-online.org). The ASN fellow’s…
I am currently writing a chapter about Living Kidney Donation “the Gold Standard”. With that in mind and two recent discussions with my co-fellows, I decided to discuss a little bit about the choice of the kidney donor…
Magnesium (Mg++) is a predominantly intracellular divalent cation which is critical for many metabolic processes and participates in >300 enzymatic reactions. It is essential for many critical transporters including the Sodium/Potassium ATPase cotransporter. Mg++ also has a critical…
Patients over 65 tend not to choose peritoneal dialysis for a host of reasons, not the least of which is PD is underutilized in the US in general. However, a recent study suggests that PD may be preferable…
Almost one year ago, Nate posted here about the results of a large GWA study of chronic kidney disease by Kottgen et al. This project was the result of a collaboration between 4 groups, and produced many exciting…
A colleague of mine at another academic institution recently informed me about a patient that had been admitted to the ICU with organophosphate poisoning. In spite of aggressive treatment, the patient remained critically ill with multiorgan dysfunction and…
Population-wide salt reduction is gaining increased media and political attention over the last few years. The most notable example is the National Salt Reduction Initiative (NSRI) spearheaded by New York City Mayor Michael Bloomberg. This initiative was unveiled…
I recently saw a patient in clinic who had sustained a head injury and developed hyponatremia that persisted after discharge. In his chart was a great deal of debate over the cause of his hyponatremia: SIADH or cerebral…
For the past 5 years, alloantibody measurement has become a standard of practice in recipients of kidney transplants experiencing worsening allograft function. This week, I admitted a patient who had a rising creatinine and on biopsy mild-moderate interstitial…
Monoclonal gammopathies generally arise from an abnormal clone that has developed from a single cell of B-cell lineage. The monoclonal protein can be intact immunoglogulin (often associated with free light chain), free light chain (FLC) in isolation, or…