Anti-Nephrin Antibodies in Minimal Change Disease
Approach to the Patient with Peritoneal Dialysis Catheter Dysfunction- Part 1
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Conferences, Courses, & Grants
FOAMed
Interventional Nephrology Series
Focus on Point-of-Care Ultrasound in Nephrology (POCUN) Series
Kidney Biopsy of the Month Series
World Kidney Day: Top 10 List
Nephron Power and Precious Bodily Fluids have nice kidney-related Top 10 lists for World Kidney Day. Here’s our list. 10. One kidney= winning, two kidneys= bi-winning 9. Most successful solid organ transplant. Living donor transplant is a…
PPI-Associated Hypomagnesemia
At renal grand rounds today, we heard about a case of severe hypomagnesemia in a patient who was on chronic omeprazole therapy. While the etiology of the low Mg2+ was likely multifactorial, I was surprised to find out…
PD – causes of blood in the dialysate
A recent post got me thinking of the differential diagnosis of blood-stained peritoneal dialysis effluent. I thought it would be interesting to share some of the differentials and to remember that the Tenchkoff catheter can truly be a…
Thrombosis and the nephrotic syndrome
Should patients with nephrotic syndrome (NS) be anticoagulated? Is there any level of proteinuria or albumin at which we should be especially concerned? The rates of venous thromboembolism (VTE) have ranged from 8-44% in observational studies and it…
Pregnancy in the Dialysis Patient
While recently reading about hypogonadism in the dialysis population, I came across this review on the pregnancy outcomes in women on dialysis, summarizing observational studies published between 1995 and 2009. I have participated in only a few pregnancy-planning…
Pendrin – role in distal bicarbonate secretion
There are two major types of intercalated cell in the collecting duct of the nephron – the alpha and beta intercalated cells. We are probably most familiar with the alpha intercalated cells in terms of acid-base handling by…
Measures of dialysis dose
As previously discussed on RFN, the urea Kt/V is a measure of dialysis dose that is related to patient outcome. There are several different Kt/Vs encountered in the dialysis literature. spKt/V = single pool eKt/V = equilibratedstdKt/V =…
Cut out the salt
Cutting back your salt intake is an effective way to reduce systolic and diastolic blood pressure and decrease your risk of dying from cardiovascular disease. The current guidelines suggest that we should reduce our dietary sodium intake to…
Whole Lot of Pressure
The maintenance of mean arterial pressure to prevent tissue dysoxia and conserve organ function is central to the management of the critically ill. In patients with increased capillary permeability this is often achieved by administration of large volumes…
Fabry’s Disease – modes of inheritance
Just a quick piece to review the inheritance pattern of Fabry’s disease, a relatively rare, but under-recognized cause of End-Stage Kidney Disease in adults. Fabry’s disease is an X-linked recessive disease, caused by a defect in the gene…