Jessica Faulkner, PhDPostdoctoral FellowAugusta University Aldosterone production and mineralocorticoid receptor (MR) activation is a key physiological pathway promoting retention of salt and water in the distal nephron. Aldosterone is a physiological ligand of MR and MR activation leads…
Eryn DixonPostdoctoral FellowWashington University School of Medicine in St. Louis Uric acid is the final metabolic byproduct of purine nucleotide breakdown (Figure 1a) and its accumulation causes hyperuricemia, which is highly prevalent and heritable. The major consequence of…
Casey DerellaPhD CandidateAugusta University Exercise and physical activity of any kind provide a substantial number of health benefits. In fact, the 2018 Physical Activity Guidelines from the American College of Sports Medicine (ACSM) recommend that some exercise is…
Music City USA is home to The Grand Ole Opry, The Music Hall of Fame and from October 31st to November 2nd, was home to the 2019 North American Cystic Fibrosis Conference (NACFC). More than 5,000 researchers and…
The kidney is all about balance; specifically the balance of fluid and electrolytes. This is in the face of sometimes an incredible onslaught of perturbations in homeostasis. To accomplish this impressive feat, the kidney is equipped with a…
As an avid spicy-food eater, I quickly learned the many home-remedies to help with the dreaded heartburn that often accompanies my jalapenos and hot wings. My secret? Well, without fail, a spoonful of Arm & Hammer baking soda…
Scientific technology is advancing quicker than ever before. Something I never thought I would be saying in my lifetime is that science now has the technology to create an Organ-On-A-Chip. An Organ-On-A-Chips is an engineered in vitro modelled…
Drug related adverse events may not be uncovered until new therapies have been on the market for many years and used among a wider patient population than in the initial clinical trials. Downing and colleagues summarized that, during…
Understanding chronic kidney disease (CKD), and its associated health risks, has been a priority for clinical and basic researchers alike. For years, the role of serum uric acid levels in CKD as a marker or causal factor have…
Hypertension is commonly associated with chronic kidney disease (CKD). The combination of hypertension and CKD together make for a BIG clinical problem. The last two decades have seen research focused on many potential causative pathways linking both hypertension…