Anti-Nephrin Antibodies in Minimal Change Disease
Approach to the Patient with Peritoneal Dialysis Catheter Dysfunction- Part 1
Want to write a case report? RFN has you covered with a list of journals to choose from
Have a Nephrology Question? There Might Be A #Tweetorial For That!
Conferences, Courses, & Grants
FOAMed
Interventional Nephrology Series
Focus on Point-of-Care Ultrasound in Nephrology (POCUN) Series
Kidney Biopsy of the Month Series
Differentiating Familial Hypocalciuric Hypercalcemia from Primary Hyperparathyroidism
The close relationship between extracellular (free) calcium concentration and parathyroid hormone (PTH) is tightly sensed by the calcium-sensing receptor (CaSR) expressed at the membrane of parathyroid cells. This control is so well regulated that even a small increase…
Parathyroid Imaging in Patients with Kidney Disease
Learning points Anatomical variation is high in parathyroid glands In medication resistant hyperparathyroidism associated with kidney disease, surgical exploration is key. Imaging is a useful adjunct to localise ectopic or supernumerary parathyroid glands Hyperparathyroidism causes bone resorption, calcific…
Kidney Replacement Therapies for Patients with Acute Neurological Injury
The incidence of acute brain injury, both ischemic and hemorrhagic stroke, is increasing in patients with end-stage kidney disease (ESKD). Risk factors include older age and co-morbidities requiring long-term systemic anticoagulation. Patients with acute traumatic brain injury develop…
Mutations in Type IV Collagen and Their Clinical Significance in Kidney Disease
One in every 10 cases of chronic kidney disease (CKD) may be attributable to a single gene mutation. Read that again. One in every 10 cases. Wow. That was a shock to me. It took me a few…
Medical Decision Making: Time to Get Acquainted with our Biases
My Commission Bias The long awaited PEXIVAS trial was finally published. I was excited to prepare and present this landmark paper at our departmental journal club.The discussion was fascinating until I started realizing that I was fighting hard…
Regional Citrate Anticoagulation in CRRT
In continuous renal replacement therapy (CRRT), the coagulation cascade is activated due to blood contact with the extracorporeal circuit. Therefore, anticoagulation is often required during CRRT to prevent premature clotting and maintain circuit patency. Unfractionated heparin has been…
SONAR: Endothelin Blockade in Diabetic Kidney Disease
More than 30-million Americans are living with diabetes and 90% of these people have type 2 diabetes mellitus (DM2). There are numerous complications associated with long-term diagnosis of DM2, with a prominent concern being the development of impaired…
The CREDENCE Trial: Less ESKD in Diabetes “Up Around the Bend”?
In April of this year, the highly-anticipated CREDENCE Trial was presented (and live-streamed) at the International Society of Nephrology (ISN) World Congress of Nephrology in Australia and simultaneously published in NEJM. But before we start dusting off our…
The Game of Boards: Examination (preparation) is Coming
As a resident, I received one of the most enduring pieces of advice from a friend who had recently sat through the American Board of Internal Medicine (ABIM) Nephrology Board examination. “You’re already late to study for it,…
Transition To Fellowship & Faculty: Challenges & Solutions
It’s almost the end of this academic year and July 1st is just around the corner. Whether you are an internal medicine resident moving on to a nephrology fellowship or a senior nephrology fellow about to become an…