A 20-year-old female had Henoch-Schönlein purpura since age 9 leading to ESRD. She underwent kidney transplantation in 2018 from a live donor (mother) and received induction immunosuppression with thymoglobulin (100 mg once) followed by maintenance with tacrolimus (6…
Benjamin Abelow’s book: The Painless Guide to Mastering Clinical Acid-Base is available again as a free download in recognition of the new class of incoming nephrology fellows. We have highlighted this book in the past. It is a…
Congratulations to the incoming class of Nephrology fellows! I’m one of you! I went to way too many interviews and had the pleasure of meeting several passionate nephrologists and fellows. I’m confident that there are a lot of…
The PRESERVE Trial, which was recently published in the NEJM was a large study of a variety of preventive measures for contrast-induced nephropathy. It used a 2×2 factorial design to test the efficacy of NaHCO3 vs. normal saline…
The next session of GlomCon’s Nephropathology Essentials will be held this Tuesday, June 12th at 11 am EDT. Dr. Helmut Rennke will be leading the session which will focus on Minimal Change Disease and FSGS (see below for…
One of the things that I always highlight when teaching fellows and residents is the importance of appropriate drug dosing for patients on dialysis and one of the drugs that is most often inappropriately dosed in my experience…
The goal of the GlomCon Teaching Platform is to enable Nephrologists, Nephropathologists, and trainees in Medicine, Nephrology, and Pathology to connect with each other to 1) Discuss challenging cases, 2) Share clinical experiences and 3) Obtain the expertise of participating…
Recently the FDA approved one of the newer exchange resins (Lokelma, ZS-9) for the treatment of hyperkalemia. (Veltassa, Patiromer), a calcium based cation exchange resin, was recently developed and approved since 2015 for the treatment of hyperkalemia. These…
Hydroxocobalamin is an antidote that was recently approved by the FDA in 2006 for the treatment of cyanide poisoning. For decades, cyanide poisoning has historically been treated using the cyanide antidote kit that contained a concoction of amyl…
Donor specific Antibodies (DSA) are one of the established biomarkers for predicting antibody mediated rejection (ABMR). This blog is a short synopsis on DSA and their complex characteristics in kidney transplantation. DSA may be preformed (before transplantation) or de-novo…