Anti-Nephrin Antibodies in Minimal Change Disease
Approach to the Patient with Peritoneal Dialysis Catheter Dysfunction- Part 1
Want to write a case report? RFN has you covered with a list of journals to choose from
Have a Nephrology Question? There Might Be A #Tweetorial For That!
Conferences, Courses, & Grants
FOAMed
Interventional Nephrology Series
Focus on Point-of-Care Ultrasound in Nephrology (POCUN) Series
Kidney Biopsy of the Month Series
Tubulointerstitial disease
ANATOMYThe tubulointerstial tissue is composed of cortex and medulla. The cortex has type 1 cells resembling fibroblasts and produces Epo. Type 2 cells in the cortex resemble dendritic cells capable of Ag presentation. Furthermore the cortex contains types…
Should we give up on anti-B-cell antibody therapy in the treatment of lupus nephritis?
For those of us managing patients with active lupus nephritis, the promise of a safe new therapy five years ago – anti-CD20 monoclonal antibody therapy against B cells- seemed like a breath of fresh air. A number of…
Mmm, let’s try rituximab
Mixed cryoglobulinemia (MC) is a systemic vasculitis in which B cell clones produce IgM with rheumatoid factor activity. The disease can range in severity from isolated skin lesions to full blown renal and neurological involvement. Most patients are…
Water treatment in dialysis- more than a Brita filter
And now for something totally exciting—a post on water treatment in dialysis. Dr Daniel Coyne of Washington University gave a great review on this topic at the Brigham Renal Board Review course this week. Here is the basic…
Adult-Onset dense deposit disease
We recently saw a case of adult-onset dense deposit disease (DDD) at pathology conference. DDD is rare, affecting 1-3 per million people. For historical reasons it has been classified under the membranoproliferative subgroup of disease patterns (as type…
Warfarin-induced AKI
We have recently posted about problems using warfarin in renal patients. On a similar note, I was recently involved in the care of a 58-year-old African-American patient who presented with oliguric AKI and a supratherapeutic INR level of…
Chronic dialysis exposure during nephrology fellowship
Much of medical residency training in the US is centered in the hospital. This is also true of many of the fellowship programs in internal medicine. As we have seen a continual increase in the number and acuity…
I think we need to have a talk about your diet
The picture above comes from a case report in KI where a PD patient presented with hypertension and edema. She was normally compliant and a plain film of her abdomen was performed to make sure that her catheter…
Boost it up!
Dealing with patients on dialysis can be challenging. In addition to the management of many comorbidities, nephrologists have to go down a list similar to a pilot’s checklist. Those include dialysis adequacy, access, electrolyte balance, fluid status, BP…
Board Review; Pregnancy answer
Each of the following choices is expected to occur during pregnancy except for A and D. Let’s go through each of the possible choices. A. This in partially incorrect. Hyperventilation (with resultant hypocapnea, not hypercapnea) occurs during pregnancy…