Anti-Nephrin Antibodies in Minimal Change Disease
Approach to the Patient with Peritoneal Dialysis Catheter Dysfunction- Part 1
Want to write a case report? RFN has you covered with a list of journals to choose from
Have a Nephrology Question? There Might Be A #Tweetorial For That!
Conferences, Courses, & Grants
FOAMed
Interventional Nephrology Series
Focus on Point-of-Care Ultrasound in Nephrology (POCUN) Series
Kidney Biopsy of the Month Series
New contributors to the Renal Fellow Network
I’d like to welcome the following new contributors to the Renal Fellow Network, who will begin writing this week. Between them, they have a wide range of clinical expertise and research interests. I’m confident that their contributions will…
A Man’s Best Friend
I’m sure many of you have a pet dog. Well, as Rover quietly licks himself in the corner, few would believe that he may hold the key to unlocking the genetic secrets of human disease, as suggested by…
Continuation of Renal Fellow Network
Thank you to everyone who has made contact with the Renal Fellow Network over the past week or so. Your outpouring of love and support has been a great comfort to Nate’s family and friends at this difficult…
Tamm-Horsfall Protein and Kidney Disease
Tamm-Horsfall protein (THP), or uromodulin, is a glycoprotein secreted by the renal epithelium, best known as the proteinacious framework of all urinary casts. It’s function in health is an enigma, but prevention of bacterial colonization of the urinary…
Warfarin and Vascular Calcification
Warfarin has recently been associated with an increased risk of stroke in ESRD patients with atrial fibrillation. This makes the decision whether to initiate warfarin therapy in dialysis patients with atrial fibrilltion anything but clear cut. Add to…
The trials of a lab rat…
I was on the phone to one of my friends the other day. He’s a renal fellow currently doing lab-based research in Boston. He’s been having a difficult time of it lately, with none of his experiments working…
Rituximab in Refractory Lupus Nephritis
Linking up nicely with Nate’s rituximab post from this Tuesday, I wanted to mention a patient with lupus nephritis whom I saw in clinic this week. She had had horrendous renal disease, as seen on the three kidney…
Glomerular Density and Predicting Progression in IgA Nephropathy
IgA nephropathy (IgAN) is an unpredictable beast, and identifying patients who will go on to develop progressive disease can be challenging. The classic predictors of progression, namely heavy proteinuria, CKD, glomerular sclerosis and tubulointerstitial fibrosis, are themselves just…
Bortezomib in Myeloma Cast Nephropathy
Bortezomib is a proteosome inhibitor used primarily in the treatment of relapsed myeloma. However, it is increasingly being used in the management of myeloma cast nephropathy (MCN). Bortezomib binds to, and inhibits the function of, the 26S proteosome…
Polycystic Kidney Disease, mTOR and Sirolimus
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by the gradual enlargement of multiple fluid filled cysts in both kidneys, which compress and destroy normal adjacent nephrons, typically resulting in ESRD by the fifth decade of life. Management…