For lovers of an underdog, the story of Tamm Horsfall protein is one of the coolest in science. Discovered in the 1950s, Tamm Horsfall protein was acknowledged but largely ignored for decades, the quirky fun uncle of the…
Hey Neph Fellows, You made it to Day 1 of Nephrology Fellowship! We’ve put together 10 tips to help as you embark on this exciting journey. Good luck and when in doubt, spin that urine. Get excited. This…
Damage to the glomerular basement membrane allows plasma lipids to enter the urinary space. These lipids may appear in various forms, either as free lipid droplets, lipid casts, oval fat bodies, and/or as cholesterol crystals. In most cases,…
Elevated intracranial pressure (ICP) is a neurologic emergency that is associated with poor outcomes. It may be caused by traumatic brain injury, intracerebral infarction or hemorrhage, subarachnoid hemorrhage, and CNS tumors. Mannitol has long been the first-line osmotic…
Welcome to the 9th case of the Skeleton Key Group, a team of twenty -odd nephrology fellows who work together to build a monthly education package for Renal Fellow Network. The cases are actual cases (without patient identifying information) that…
This Wednesday, June 17th 2020 ASN invites everyone to join in (virtually) to celebrate the Nephrology Fellowship graduating class of 2020. Below are the list of speakers scheduled. Should be a great program.
Peritoneal dialysis (PD) catheters are one of the most successful long-term transcutaneous access devices ever used in medical practice. The catheter, if successfully placed can provide successful dialysis for years. For the above to be accomplished, various components…
The close relationship between extracellular (free) calcium concentration and parathyroid hormone (PTH) is tightly sensed by the calcium-sensing receptor (CaSR) expressed at the membrane of parathyroid cells. This control is so well regulated that even a small increase…
Learning points Anatomical variation is high in parathyroid glands In medication resistant hyperparathyroidism associated with kidney disease, surgical exploration is key. Imaging is a useful adjunct to localise ectopic or supernumerary parathyroid glands Hyperparathyroidism causes bone resorption, calcific…
Several drugs, mainly antimicrobial or antiviral agents, can cause transient crystalluria, in isolation or in conjunction with other urinary abnormalities and a wide range of clinical implications. The factors favoring the formation of drug crystals are drug overdose,…