Attention Nephrology Fellows: Compete in the 2nd Annual NephMadness Invitational Tournament at the 2025 NKF Spring Clinical Meeting!
Onconephrology Early Program at ASN , titled “Onconephrology: Cancer, Its Treatments and the Kidneys.”
Leucine Crystals in the Urine – Still enigmatic after more than 150 years
Wanted: RFN Fellow Editor (Application Due 11/1)
Kidney Comics: The Nephron Factory
Skeleton Key Group Case #35: Rhabdo Fiasco
2025 NephSIM Nephrons: Application Due 11/1 (For Medical Students & Residents)
Advances in Peritoneal Dialysis Symposium: 9/27 (In-Person)
Skeleton Key Group Case #34: Adrenal Insufficiency- A Salty Saga
Kidney Biopsy of the Month: Glomerular diseases with organized deposits
Our focus on myeloma related disorders continues- view previous posts here. Glomerular diseases with organized deposits belong to a broad group of paraprotein-related diseases that affect the kidneys. The presence of substructure or organization to deposits is often…
Kidney Biopsy of the Month: Monoclonal Immunoglobulin Deposition Disease
We continue a focus on features of myeloma kidney. Previous posts available here. Monoclonal immunoglobulin deposition diseases (MIDD) are systemic disorders characterized by deposition of monoclonal immunoglobulins involving all components of the renal parenchyma including glomerular and tubular…
Kidney Biopsy of the Month: Light Chain Proximal Tubulopathy with Crystals (LCPT)
We continue the focus on Myeloma kidney, which started last month with Light Chain Cast Nephropathy. This month the emphasis is on Light Chain Proximal Tubulopathy with Crystals (LCPT)- a distinct entity. Terminology Chronic tubulointerstitial nephropathy caused by…
Kidney Biopsy of the Month: Light Chain Cast Nephropathy
Introduction Light chain cast nephropathy (LCCN), not to be confused with light chain deposition disease (LCDD), is also known as myeloma cast nephropathy or myeloma kidney; and is one of the many renal complications of multiple myeloma. Patients…
Kidney Biopsy of the Month: IgA Nephropathy
IgA nephropathy (IgAN) is the most common form of glomerulonephritis worldwide, and is responsible for ~10% of glomerulonephritis in the United States. IgA nephropathy can be primary or secondary. The pathophysiology of primary IgAN is complex and incompletely…
Kidney Biopsy of the Month – Acute Interstitial Nephritis
Acute interstitial nephritis (AIN) is a common cause of acute kidney injury (AKI), estimated to account for 15-20% of cases of AKI. The term AIN does not refer to a specific disease, but rather indicates an immune-mediated form…
Kidney Biopsy of the Month: Diabetic Nephropathy
Morphological changes due to diabetes are similar in type 1 and type 2 diabetes and can be observed in all the 4 structural compartments of the kidney: glomeruli, vessels, interstitium, and tubules. Approximately one-third of diabetics will develop…
Kidney Biopsy of the Month – The Blood Vessels
Our review of normal kidney histology concludes with the vasculature. The kidneys are richly vascular organs, receiving approximately one-quarter of the cardiac output. The renal vascular architecture is unique and complex, allowing the kidney to perform its many…
Kidney Biopsy of the Month- The Tubulointerstitium Part 2: The Medulla
Last month, we focussed on the renal cortex in the tubulointersitium, as part of the Kidney Biopsy of the Month: What is Normal series. We will now concentrate on the renal medulla, a region of the kidney sometimes…
Kidney Biopsy of the Month- The Tubulointerstitium Part 1: The Cortex
The tubulointerstitium of the kidney is broadly divided into the cortex and the medulla. These are extremely important components of the kidney, which can show a broad spectrum of changes ranging from subtle to significant, in both acute…